Abstract

IN recent years, in a study of the clinical and pathological aspects of liver disease in patients with chronic alcoholism, it was observed that acute renal failure due to papillary necrosis occurred in a significant number. None of the patients had diabetes mellitus, urinary tract obstruction, or a history of excessive use of analgesics. In a search of the literature, only five examples of the concomitant occurrence of cirrhosis and papillary necrosis were noted. Knutsen et al<sup>1</sup>mentioned that cirrhosis was present in one of 16 cases of papillary necrosis, all proven either at autopsy or in surgical specimens. Cirrhosis was mentioned as being present at autopsy in two of 14 cases of the sclerotic type of papillary necrosis reported by Schourup.<sup>2</sup>In reports of the other two patients, an elevated blood-glucose level was mentioned, so that diabetes mellitus could not be ruled out. One was an elderly

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