Abstract
Renal oncocytomas and retroperitoneal schwannomas are rare and typically benign tumors with characteristic histopathologic features. Ideal management of both renal oncocytoma and retroperitoneal schwannoma is surgical resection. We present a rare case of a 63-year-old man with multifocal renal oncocytoma and retroperitoneal ancient schwannoma which, preoperatively, masqueraded as metastatic renal cell carcinoma. Both tumors were successfully resected surgically. Immunochemistry and histopathology confirmed each diagnosis.
Highlights
Renal oncocytoma is a rare tumor accounting for approximately 4% of all solid renal masses [1]
To the best of our knowledge, the present study reports the first case of multifocal renal oncocytoma and retroperitoneal ancient schwannoma
Oncocytomas are characterized by nests of round and polygonal, highly eosinophilic cells with granular cytoplasm secondary to a high concentration of mitochondria [2]
Summary
Renal oncocytoma is a rare tumor accounting for approximately 4% of all solid renal masses [1]. While the majority of oncocytomas are benign, there have been several case reports of malignant behavior and metastasis [2, 3]. Long-term outcomes in patients with oncocytomas are highly favorable, with previous reports indicating a disease-specific survival of up to 100% [4]. Primary tumors of the retroperitoneum are uncommon. Schwannomas are thought to occur in approximately 4% of all primary retroperitoneal tumors [5]. Malignant schwannomas have been reported in the literature [6], the vast majority are benign in nature. To the best of our knowledge, the present study reports the first case of multifocal renal oncocytoma and retroperitoneal ancient schwannoma. The clinical, radiographic, and pathologic findings of this case are discussed in detail
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