Abstract
Renal net acid excretion (NAE) was determined in 2307 24-h urine samples from 566 healthy children and adolescents (285 boys, 281 girls; 2.7-18.3 years) participating in the DONALD (Dortmund Nutritional and Anthropometric Longitudinally Designed) Study. NAE is presented for 32 different age and sex groups. Before puberty there is an age-dependent increase in absolute values of NAE (mmol/day) and an age-dependent decrease in NAE related to body weight (mmol/kg per day). NAE related to body surface area (mmol/day per 1.73 m2) was independent of age with higher values in boys than in girls. In summary, body surface area is an appropriate adjustment parameter for renal NAE in the age-independent assessment of the renal acid load in German children and adolescents.
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