Renal lithium excretion in man

Abstract

ARTICLESRenal lithium excretion in manK Thomsen, and M SchouK Thomsen, and M SchouPublished Online:01 Oct 1968https://doi.org/10.1152/ajplegacy.1968.215.4.823MoreSectionsPDF (1 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformation Cited ByEnd-proximal tubule phosphate concentration increases as GFR falls in humans: measurement by means of a lithium clearance-based methodology13 May 2022 | Nephrology Dialysis Transplantation, Vol. 71Medical Management of Glaucoma23 April 2022Lithium carbonate: Updated reproductive and developmental toxicity assessment using scientific literature and guideline compliant studiesToxicology, Vol. 461The impact of caffeine consumption on clinical symptoms in patients with bipolar disorder: A systematic review28 September 2020 | Bipolar Disorders, Vol. 23, No. 3Caffeine Restrictions in Inpatient Psychiatric Settings: Precipitating Withdrawal?11 October 2019 | Journal of Addiction Medicine, Vol. 14, No. 4Medical Management of Glaucoma8 September 2021Effect of renal ischemia on urinary excretion of lithium in rats28 November 2018 | Biopharmaceutics & Drug Disposition, Vol. 39, No. 9Urinary reference ranges and exposure profile for lithium among an Italian paediatric populationScience of The Total Environment, Vol. 619-620Nonlinear disposition of lithium in rats and saturation of its tubular reabsorption by the sodium-phosphate cotransporter as a cause12 January 2018 | Biopharmaceutics & Drug Disposition, Vol. 39, No. 2Take care when using lithium with other drugs, as clinically relevant interactions may occur22 November 2016 | Drugs & Therapy Perspectives, Vol. 33, No. 2Lithium25 June 2017The Pharmacokinetics of Lithium26 November 2016Effect of Excessive Coffee Consumption on the Clinical Course of a Patient With Bipolar DisorderClinical Neuropharmacology, Vol. 40, No. 4Caffeine intake antagonizes salt sensitive hypertension through improvement of renal sodium handling12 May 2016 | Scientific Reports, Vol. 6, No. 1Drug Interactions with Lithium: An Update2 March 2016 | Clinical Pharmacokinetics, Vol. 55, No. 8Foscarnet, an inhibitor of the sodium-phosphate cotransporter NaPi-IIa, inhibits phosphorylation of glycogen synthase kinase-3β by lithium in the rat kidney cortexDrug Metabolism and Pharmacokinetics, Vol. 31, No. 3Stabilization of the Serum Lithium Concentration by Regulation of Sodium Chloride Intake: Case ReportYAKUGAKU ZASSHI, Vol. 136, No. 3Clinically Significant Interactions with Mood Stabilisers3 March 2016LithiumLithium27 September 2016Caffeine-induced diuresis and natriuresis is independent of renal tubular NHE3Robert A. 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loopKidney International, Vol. 44, No. 2Drug nephrotoxicity — The significance of cellular mechanismsClearance Techniques1 January 2011Evaluation of nephrotoxicity secondary to cytostatic agentsCritical Reviews in Oncology/Hematology, Vol. 13, No. 3Lithium absorption prevented by sodium polystyrene sulfonate in volunteersAnnals of Emergency Medicine, Vol. 21, No. 11Role of nitric oxide in mediating renal response to volume expansion.Hypertension, Vol. 19, No. 6_pt_2RENAL HANDLING OF ENDOGENOUS LITHIUM IN EXPERIMENTAL DIABETES MELLITUS IN THE RATClinical and Experimental Pharmacology and Physiology, Vol. 19, No. 3Endogenous lithium determination in blood plasma and urine by isotope dilution mass spectrometry and preliminary isolation of lithium fraction using paper chromatographyBiological Mass Spectrometry, Vol. 21, No. 2Chronopharmacokinetics and Chronotoxicity of Lithium in Mice Eating Normal and Low-Sodium Diets1 September 2010 | Chronobiology International, Vol. 9, No. 2Insulin increases sodium reabsorption in diluting segment in humans: Evidence for indirect mediation through hypokalemiaKidney International, Vol. 40, No. 2Cyclic Antidepressants, Lithium, and Neuroleptic AgentsEmergency Medicine Clinics of North America, Vol. 9, No. 1Renal tubular sodium handling and plasma atrial natriuretic peptide, renin activity and aldosterone in untreated men under normal living conditionsEuropean Journal of Clinical Investigation, Vol. 21, No. 1Renal Elimination of LithiumEffects of felodipine on the dog kidney: A lithium clearance study29 March 2011 | Scandinavian Journal of Clinical and Laboratory Investigation, Vol. 51, No. 2Loop diuretics reduce lithium reabsorption without affecting bicarbonate and phosphate reabsorptionActa Physiologica Scandinavica, Vol. 140, No. 1Tubular sodium handling in cirrhotic patients with ascites as analysed by the renal lithium clearance method28 June 2008 | European Journal of Clinical Investigation, Vol. 20, No. 3Selective peripheral dopamine-1 receptor stimulation. Differential responses to sodium loading and depletion in humans.Hypertension, Vol. 15, No. 6_pt_2Psychopharmacology in Patients with Hepatic and Gastrointestinal Disease1 January 1995 | The International Journal of Psychiatry in Medicine, Vol. 20, No. 2Effect of chronic oral furosemide administration on the 24-hour cycle of lithium clearance and electrolyte excretion in humansEuropean Journal of Clinical Pharmacology, Vol. 38, No. 3The use of lithium in the medically illGeneral Hospital Psychiatry, Vol. 12, No. 2Tubular site of renal sodium retention in ascitic liver cirrhosis evaluated by lithium clearance28 June 2008 | European Journal of Clinical Investigation, Vol. 20, No. 1Analysis of the relation between lithium clearance and sodium clearance in rats29 March 2011 | Scandinavian Journal of Clinical and Laboratory Investigation, Vol. 50, No. 2A lithium clearance study of sodium reabsorption at the proximal tubule in liver cirrhosis with ascitesGastroenterologia Japonica, Vol. 24, No. 5Evaluation of lithium clearance as a marker of proximal tubule sodium handlingKidney International, Vol. 36, No. 1Red-cell sodium-lithium countertransport and fractional excretion of lithium in normal and hypertensive humans.Hypertension, Vol. 13, No. 3Drug Induced Renal Effects of Cyclosporine, Aminoglycoside Antibiotics and Lithium: Extrapolation of Animal Data to ManThe genetics of essential hypertensionThe acute effect of acetazolamide on glomerular filtration rate and proximal tubular reabsorption of sodium and water in normal man8 July 2009 | Scandinavian Journal of Clinical and Laboratory Investigation, Vol. 49, No. 6The effects of intravenous theophylline infusion versus intravenous Sodium Bicarbonate infusion on Lithium clearance in normal subjectsPsychiatry Research, Vol. 25, No. 2Low dose dopamine in lithium poisoning.26 July 2012 | British Journal of Clinical Pharmacology, Vol. 26, No. 2Relationship between plasma concentration, saliva concentration and urinary excretion rate of lithium in manInternational Journal of Pharmaceutics, Vol. 43, No. 1-2Psychotropic Drug Interactions in the Patient with Late-Onset Depression or PsychosisPsychiatric Clinics of North America, Vol. 11, No. 1Extracorporeal techniques in the treatment of exogenous intoxicationsKidney International, Vol. 33, No. 3Clinical Features and Management of Lithium Poisoning27 November 2012 | Medical Toxicology, Vol. 3, No. 1The influence of body posture on lithium clearance8 July 2009 | Scandinavian Journal of Clinical and Laboratory Investigation, Vol. 48, No. 6EFFECTS OF CYCLOSPORIN A, GENTAMICIN AND FUROSEMIDE ON RAT RENAL FUNCTION: A LITHIUM CLEARANCE STUDYClinical and Experimental Pharmacology and Physiology, Vol. 14, No. 11-12Prevalence, Pathogenesis, and Treatment of Renal Dysfunction Associated With Chronic Lithium TherapyAmerican Journal of Kidney Diseases, Vol. 10, No. 5Lithium MonitoringClinics in Laboratory Medicine, Vol. 7, No. 3Lithium clearance during the paradoxical natriuresis of hypotonic expansion in manKidney International, Vol. 32, No. 3Lithium: Long-term effects on the kidney.Acta Psychiatrica Scandinavica, Vol. 76, No. 2Self-poisoning and Therapeutic Intoxication with Lithium6 September 2016 | Human Toxicology, Vol. 6, No. 4Drug-Antacid Interactions: Assessment of Clinical Importance14 February 2017 | Drug Intelligence & Clinical Pharmacy, Vol. 21, No. 7-8Lichen sclerosus et atrophicus in children misdiagnosed as sexual abuse.BMJ, Vol. 294, No. 6584Lithium Pharmacology and PhysiologyLithium: Clinical ConsiderationsInteraction of Drugs and NutrientsAdrenergic Receptors and Sodium Reabsorption in Normotensive Subjects as Related to Salt Sensitivity3 July 2009 | Clinical and Experimental Hypertension. 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Monitoring30 August 2016 | Drug Intelligence & Clinical Pharmacy, Vol. 13, No. 9A micropuncture study of the renal handling of lithiumPfl�gers Archiv European Journal of Physiology, Vol. 380, No. 2Sweat Lithium in Manic-Depression29 January 2018 | British Journal of Psychiatry, Vol. 134, No. 4Lithium IntoxicationPsychiatric Annals, Vol. 8, No. 9Using antidepressants effectively7 July 2016 | Postgraduate Medicine, Vol. 64, No. 2Problems with Drug Interactions in Treating Brain DisordersPsychiatric Clinics of North America, Vol. 1, No. 1Lithium und EndokriniumPrecipitating factors and renal mechanisms in lithium intoxicationGeneral Pharmacology: The Vascular System, Vol. 9, No. 2Severe Neurotoxicity and Lithium Therapy25 September 2008 | Clinical Toxicology, Vol. 13, No. 4THE EFFECTS OF LITHIUM ON ATPase ACTIVITY IN SUBCELLULAR FRACTIONS FROM RAT BRAINJournal of Neurochemistry, Vol. 29, No. 5Chronic renal lesions following long-term treatment with lithiumKidney International, Vol. 12, No. 3Distal nephron function of the rat during lithium chloride infusionKidney International, Vol. 12, No. 1The Renal Handling of Lithium: Relation Between Lithium Clearance, Sodium Clearance and Urine Flow in Rats with Diabetes Insipidus13 March 2009 | Acta Pharmacologica et Toxicologica, Vol. 40, No. 4The Renal Handling of Lithium: Relation Between Lithium Clearance, Sodium Clearance and Urine Flow in Rats with Diabetes Insipidus13 March 2009 | Acta Pharmacologica et Toxicologica, Vol. 40Frusemide and Lithium Toxicity14 January 2019 | Anaesthesia and Intensive Care, Vol. 5, No. 1The cardiovascular effects of lithium in manThe American Journal of Medicine, Vol. 61, No. 5The role of α- and β-adrenergic effects in the action of adrenaline on renal lithium elimination in adrenalectomized ratsEuropean Journal of Pharmacology, Vol. 36, No. 1ADVERSE REACTIONS ASSOCIATED WITH MOOD-ALTERING DRUGSPsychiatric Annals, Vol. 5, No. 115 The Medicinal Chemistry of LithiumClinical Pharmaceutical Aspects of Lithium Therapy30 August 2016 | Drug Intelligence & Clinical Pharmacy, Vol. 9, No. 1Reabsorption of lithium and phosphate by the rat kidney: Role of the parathyroidsKidney International, Vol. 5, No. 3Renal Lithium Clearance during Dehydration and Rehydration with Water or 0.9% NaCl in the RatActa Physiologica Scandinavica, Vol. 90, No. 2Farmakokinetikens Praktiske Konsekvenser: Belyst Ved Lithiumbehandlingens Styrings- Og Kontrolproblemer12 July 2009 | Nordisk Psykiatrisk Tidsskrift, Vol. 28, No. 6The Effect of Sodium Chloride on Kidney Function in Rats with Lithium Intoxication13 March 2009 | Acta Pharmacologica et Toxicologica, Vol. 33, No. 2PHARMACOKINETICS OF LITHIUM IN MANIC-DEPRESSIVE PATIENTSActa Psychiatrica Scandinavica, Vol. 49, No. 3Acute renal failure and lithium intoxicationPostgraduate Medical Journal, Vol. 49, No. 570Aminophylline — Review of Clinical Use5 December 2017 | Drug Intelligence & Clinical Pharmacy, Vol. 7, No. 4Lithium-induced ADH resistance in toad urinary bladdersKidney International, Vol. 3, No. 3Pharmacology—The Biology of LithiumPharmacology—Lithium Absorption, Distribution, Renal Handling, and Effect on Body ElectrolytesPharmacology—Toxicology of the Lithium IonLithium25 September 2008 | Clinical Toxicology, Vol. 6, No. 2Mechanisms of renal lithium handling and their relationship to mineralocoticoids: A dissociation between sodium and lithium ionsJournal of Psychiatric Research, Vol. 8, No. 2The Use of Lithium in Psychiatry21 October 2008 | CRC Critical Reviews in Clinical Laboratory Sciences, Vol. 2, No. 2Individual differences in serum levels of lithium in human subjects receiving fixed doses of lithium carbonate. relation to renal lithium clearance and body weightPharmacologia Clinica, Vol. 2, No. 4Lithium effect on plasma glucagon, liver phosphorylase-a and liver glycogen in ratsJournal of Psychiatric Research, Vol. 8, No. 1Acute lithium poisoning.Postgraduate Medical Journal, Vol. 46, No. 540Pharmacological and Clinical Problems of Lithium Prophylaxis29 January 2018 | British Journal of Psychiatry, Vol. 116, No. 535Lithium in hazardous circumstances with one case of lithium toxicityComprehensive Psychiatry, Vol. 11, No. 3Lithium Carbonate26 April 2017 | Canadian Psychiatric Association Journal, Vol. 15, No. 2Acute Lithium ToxicityNew England Journal of Medicine, Vol. 281, No. 24RENAL LITHIUM ELIMINATION IN MAN AND ACTIVE TREATMENT OF LITHIUM POISONINGActa Psychiatrica Scandinavica, Vol. 44, No. S207Lithium as an indicator of proximal sodium reabsorptionPfl�gers Archiv European Journal of Physiology, Vol. 308, No. 2 More from this issue > Volume 215Issue 4October 1968Pages 823-827 Copyright & PermissionsCopyright © 1968 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1968.215.4.823PubMed5676383History Published online 1 October 1968 Published in print 1 October 1968 Metrics