Renal involvement in scleroderma.

Abstract

Case Reports1 March 1960RENAL INVOLVEMENT IN SCLERODERMAE. C. KHOO, M.D., THOMAS A. STUMP, M.D.E. C. KHOO, M.D.Search for more papers by this author, THOMAS A. STUMP, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-52-3-717 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough it is well recognized that scleroderma is a generalized disease, the specific pathologic changes in the kidneys have only recently been emphasized. In 1952 Moore and Sheehan1 described the lesions in the renal cortices of three patients dying from renal involvement by scleroderma. Since then several reports have stressed renal involvement as a cause of death in scleroderma.2, 3, 4, 5, 6.The following case, together with a summary of cases reported in the English literature, illustrates the striking similarity in clinical course and pathologic findings. Only cases with adequate descriptions of clinical course and autopsy findings have been...Bibliography1. MooreSheehan HCHC: The kidney of scleroderma, Lancet 1: 68-70, 1952. CrossrefMedlineGoogle Scholar2. HanniganHanniganScott CAMHEL: Scleroderma of the kidneys, Am. J. Med. 20: 793-797, 1956. CrossrefMedlineGoogle Scholar3. RodnanSchreinerBlack GPGERL: Renal involvement in progressive systemic sclerosis (generalized scleroderma), Am. J. Med. 23: 445-462, 1957. CrossrefMedlineGoogle Scholar4. FredRambo HLON: Acute renal failure due to scleroderma kidney disease, Arch. Int. Med. 100: 813-818, 1957. CrossrefGoogle Scholar5. Case records of Massachusetts General Hospital: Case #43341, New England J. Med. 257: 378-383, 1957. CrossrefMedlineGoogle Scholar6. RottenbergSlocumbEdwards ENCEJE: Cardiac and renal manifestations in progressive systemic scleroderma, Proc. Staff Meet., Mayo Clin. 34: 77-80, 1959. MedlineGoogle Scholar7. PiperHelwig WNEB: Progressive systemic sclerosis, Arch. Dermat. and Syph. 72: 535-549, 1955. CrossrefGoogle Scholar8. LunsethBakerShifrin JHLAA: Chronic scleroderma with acute exacerbation during corticotrophin therapy, Arch. Int. Med. 88: 783-792, 1951. CrossrefGoogle Scholar9. Beerman H: The visceral manifestations of scleroderma. Review of recent literature, Am. J. M. Sc. 216: 458-475, 1948. CrossrefMedlineGoogle Scholar10. SharnoffCardeoStein JGHLIB: Cortisone treated scleroderma, J. A. M. A. 145: 1230-1232, 1951. CrossrefMedlineGoogle Scholar11. FisherRodnan ERGP: Pathologic observation concerning the kidney in progressive systemic sclerosis, Arch. Path. 65: 29-39, 1958. MedlineGoogle Scholar12. Clinicopathological conference: Scleroderma with congestive heart failure, Am. J. Med. 14: 231-239, 1953. CrossrefMedlineGoogle Scholar13. MathisenPalmer AKJD: Scleroderma with involvement of the heart, Am. Heart J. 33: 366-374, 1947. CrossrefMedlineGoogle Scholar14. Case records of Massachusetts General Hospital: Case #42211, New England J. Med. 254: 998-1002, 1956. CrossrefMedlineGoogle Scholar15. Zarafonetis CJ: Treatment of scleroderma, Ann. Int. Med. 50: 343-365, 1959. LinkGoogle Scholar16. CalvertOwen RJTK: True scleroderma kidney, Lancet 2: 19-22, 1956. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Indianapolis, Indiana*Received for publication August 18, 1959.From the Departments of Medicine and Pathology, Marion County General Hospital, Indianapolis, Indiana.Requests for reprints should be addressed to Thomas A. Stump, M.D., Marion County General Hospital, 960 Locke Street, Indianapolis 7, Indiana. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byProgressive systemische Sklerodermie (Sklerose)Progressive Systemic Sclerosis: Cardiac InvolvementVascular Disease in Progressive Systemic Sclerosis (Scleroderma)WALTER L. NORTON, M.D., F.A.C.P., JOHN M. NARDO, M.D.Accelerated Nephrosclerosis and Postpartum Acute Renal Failure in Normotensive PatientsRICHARD D. WAGONER, M.D., KEITH E. HOLLEY, M.D., WILLIAM J. JOHNSON, M.D., F.A.C.P.Die pathologische Anatomie der intern-medizinisch bedeutsamsten NierenkrankheitenEntwicklungslinien der Sklerodermieforschung in der GegenwartThe Kidney Function in Patients with Rheumatoid Arthritis in Relation to the Commencement of the Disease (VI)The Kidney Function in Patients with Rheumatoid Arthritis in Relation to the Commencement of the Disease (VI)Rheumatism and Arthritis Review of American and English Literature of Recent Years (Fifteenth Rheumatism Review)CHARLEY J. SMYTH, M.D., F.A.C.P., FELIX E. DEMARTINI, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., EDWARD C. FRANKLIN, M.D., DONALD F. HILL, M.D., F.A.C.P., JOSEPH LEE HOLLANDER, M.D., F.A.C.P., HOWARD L. HOLLEY, M.D., F.A.C.P., JOHN G. MAYNE, M.D., F.A.C.P., WILLIAM M. MIKKELSEN, M.D., F.A.C.P., MAX M. MONTGOMERY, M.D., F.A.C.P., CARL M. PEARSON, M.D., F.A.C.P., CHARLES L. SHORT, M.D., F.A.C.P., HUGH A. SMYTHE, M.D., F.R.C.P. (C), OTTO STEINBROCKER, M.D. 1 March 1960Volume 52, Issue 3Page: 717-728KeywordsAutopsyFibrosisHemorrhageHospital medicineKidneysLesionsNecrosisSclerodermaSteroid therapy ePublished: 1 December 2008 Issue Published: 1 March 1960 PDF downloadLoading ...