Abstract
ABSTRACT: A 10-year-old male large mixed breed dog was presented with skin ulcers and fracture on the right hind limb caused by vehicle collision. Given required limb amputation, and as being a shelter senior dog, euthanasia was requested by the owner and a complete post-mortem examination was conducted immediately after death. Gross changes were consistent with marked bilateral nephromegaly. Histopathological examination of the kidneys revealed round cells filling blood vessels. Immunohistochemically, the round cells were positive for CD3 antibody. Based on these findings, in absence of involvement of the bone marrow and peripheral blood, and inexistence of primary extravascular masses, the tumor was classified as T-cell intravascular lymphoma. To the author’s knowledge, this is the first report describing intravascular lymphoma involving the kidneys alone in a dog.
Highlights
RESUMO: Um canino, macho, de 10 anos, sem raça definida (SRD), e grande porte, chegou para atendimento apresentando fratura em membro pélvico direito devido a atropelamento por veículo automotivo
Classification), malignant angioendotheliomatosis (ZUCKERMAN et al, 2006), intravascular lymphomatosis (ZUCKERMAN et al, 2006), and systemic proliferative angioendotheliomatosis (PFLEGER & TAPPEINER, 1959), is a rare subtype of lymphoma characterised by proliferation of neoplastic lymphocytes within blood vessels, capillaries, with no or minimal involvement of the parenchyma (VALLI et al, 2002; VALLI, 2007; VALLI et al, 2016, 2017)
The aim of this report is to describe a case of intravascular lymphoma involving only the kidneys of a dog
Summary
RESUMO: Um canino, macho, de 10 anos, sem raça definida (SRD), e grande porte, chegou para atendimento apresentando fratura em membro pélvico direito devido a atropelamento por veículo automotivo. Classification), malignant angioendotheliomatosis (ZUCKERMAN et al, 2006), intravascular lymphomatosis (ZUCKERMAN et al, 2006), and systemic proliferative angioendotheliomatosis (PFLEGER & TAPPEINER, 1959), is a rare subtype of lymphoma characterised by proliferation of neoplastic lymphocytes within blood vessels, capillaries, with no or minimal involvement of the parenchyma (VALLI et al, 2002; VALLI, 2007; VALLI et al, 2016, 2017). Human intravascular lymphomas are most often consistent with B-cell origin.
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