Abstract
Clearances of inulin, p-amino hippuric acid, silicicacid, urea and osmoles were measured in 4 cows given range hay and alfalfa hay in restricted and unrestricted amounts. Inulin and p-amino hippurate clearances were not affected by the ration but did appear to be affected by level of intake. Clearances of urea and osmoles were higher with alfalfa hay than with range hay, the differences in each case being due mainly to differences in fractional reabsorption. The clearance of silicic acid closely paralleled that of inulin, suggesting that diet affected silicic acid clearance only to the extent that it altered the glomerular filtration rate. An average of 25% of filtered silicic acid was reabsorbed. Urinary recovery of injected silicic acid was usually less than 100%, indicating that sites other than the kidney were involved in clearing the blood of silicic acid. The results suggest that tubular regulation of silicic acid excretion was absent.
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