Abstract

An impressive water, sodium and chloride diuresis is described occurring in a hypertensive subject in response to emotion. Observations were made upon the creatinine, inulin and paraaminohippurate clearances and upon various urinary constituents. An increase in glomerular filtration and a diminished percentage reabsorption of water and salt occurred. It is suggested that the increase in water excretion was due to simultaneous nervous renal vasodilation (with raised glomerular filtration rate) and posterior pituitary inhibition. The increase in salt excretion probably also resulted from the raised glomerular filtration rate, and was accentuated by hypertensive tubular inadequacy.

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