Renal failure secondary to uterine prolapse

Özer Birge ,İlkan Kayar ,Ertuğrul Gazi Özbey ,Utku Akgör ,Mehmet Adıyeke ,Mustafa Erkan

doi:10.17077/2154-4751.1291

Özer Birge , İlkan Kayar + Show 4 more

Open Access

https://doi.org/10.17077/2154-4751.1291

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Abstract

Pelvic organ prolapse is a common problem in female population, and it may cause minor urological problems such as recurrent urinary system infection and voiding difficulty, as well as serious clinical problems such as advanced bilateral hydronephrosis and acute renal failure. Bilateral hydroureteronephrosis and acute renal failure secondary to pelvic organ prolapse are rarely seen. In our paper, we present the case of a 69 year old woman that developed bilateral hydroureteronephrosis, anuria and acute renal failure secondary to pelvic organ prolapse with a review of the literature.

Highlights

Pelvic organ prolapse is the bulging of uterus, bowel, rectum and vagina out of the vulva, and is commonly seen in postmenopausal women.[1]The prevalence of pelvic organ prolapse (POP) in the general population is about14%, where it increases up to 67.8% in the elderly, causing a serious public health problem.[2,3] Pelvic organ prolapse should not be viewed solely as genital organ prolapse due to the close anatomical contiguity with the lower urinary tract which may cause hydronephrosis, a serious upper tract pathology, and acute renal failure.Hydroureteronephrosis secondary to POP was first described in 1824 by Froriep.[4]
We think that a renal evaluation is required in cases with advanced pelvic organ prolapse, as in our presented case with total uterine prolapse and high creatinine levels
One of the most important hypotheses suggests that the bilateral ureters are compressed between the uterine fundus and bowel against the levator ani muscles, with this pressure being conducted to the upper urinary tract, causing a decrease in glomerular filtration rate (GFR) and, thereby a disturbance in renal functions.[11]

Summary

Introduction

Pelvic organ prolapse is the bulging of uterus, bowel, rectum and vagina out of the vulva, and is commonly seen in postmenopausal women.[1]The prevalence of pelvic organ prolapse (POP) in the general population is about14%, where it increases up to 67.8% in the elderly, causing a serious public health problem.[2,3] Pelvic organ prolapse should not be viewed solely as genital organ prolapse due to the close anatomical contiguity with the lower urinary tract which may cause hydronephrosis, a serious upper tract pathology, and acute renal failure.Hydroureteronephrosis secondary to POP was first described in 1824 by Froriep.[4].

Results

Conclusion