Abstract
Renal Failure from CastNephropathy: Role of Plasmapheresis
Highlights
In multiple myeloma renal involvement is common, occurring in 50% of the patients and is an independent predictor of poor patient survival [1]
In a systematic review of literature by Kumar et al concluded that overall survival as well as the need for dialysis is not affected by plasmapheresis in multiple myeloma patients with acute renal failure [3]
Another systematic review in patients with acute renal failure from multiple myeloma reported no benefit of plasmapheresis in renal function improvement or overall survival
Summary
In multiple myeloma renal involvement is common, occurring in 50% of the patients and is an independent predictor of poor patient survival [1]. © All rights are reserved by Adapa S, et al Renal Failure from Cast Nephropathy: Role of Plasmapheresis The evidence on the role of Plasmapheresis combined with chemotherapy alleviating renal failure by reducing the light chains load is conflicting.
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