Abstract
The most prominent advances in the management of patients with chronic renal failure and recent findings in the pathophysiology and pharmacology relevant to treatment in the perioperative period are reviewed. The treatment of uraemic anaemia with recombinant erythropoietin may reduce the need for blood transfusions. The pharmacological properties of calcium antagonists have stimulated researchers to find their therapeutic potential in patients with renal dysfunction and with hypertension. The growing shortage of kidneys for transplantation calls for improving immunosuppressive therapy of the recipients and for developing new donor programmes. The use of kidneys from donors with ceased blood circulation has been suggested.
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