Abstract
The first-in-man study of catheter based renal denervation (RDN) suggests that this novel approach is associated with sustained blood pressure reduction without serious adverse events in patients with resistant hypertension [1]. Subsequent clinical studies show that RDN reduces renal [2] and whole-body sympathetic activities [3], and exerts beneficial effects in other disease states characterized by chronic sympathetic activation, such as heart failure [4] and left ventricular hypertrophy [5]. In consideration of the association between hypertension, sympathetic activation and atrial fibrillation (AF), Pokushalov et al.
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