Renal damage resulting from idiosyncrasy to neoarsphenamine

Abstract

1.1. A review of the available literature reveals the relative infrequency of severe renal reactions following arsenical therapy.2.2. A case is presented of severe nephrosis accompanied by purpura and gastrointestinal reaction which followed the administration of a small dose of neoarsphenamine.3.3. Despite the severity of the reaction nearly complete recovery has occurred in this case.4.4. The renal injury in this instance is thought to have been due to a sensitivity reaction. Clinically, the manifestations were similar to those of nephrosis caused by bichloride of mercury and accompanying sulfonamide sensitivity.