Abstract
The kinetics of biotransformation of benzoic acid to hippuric acid during infusion in animals were studied at steady state. The contributions to the glycine conjugation of benzoic acid made by the kidney in contrast to the body as a whole were quantified by the utilization of apparent clearances, (Vel)app., and true renal clearances, (Vel)ex. Michaelis-Menten kinetics appear to describe the rate of biotransformation of both metabolic processes. The data result in estimation of the in vivo Km and Vmax. values.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
