Abstract
The nephropathy and renal complications of sickle cell disease are associated with various events such as hypoxic or ischemic conditions and reperfusion injury. Erythrocyte sickling occurs following these events and renal medullary acidosis.
Highlights
The incidence rate of sickle cell disease (SCD) is estimated at 300 000 births per year
Hemoglobin SS (HbSS) disease is the most common type of SCD and approximately one-third of SCD patients are heterozygous for hemoglobin SD (HbSD) (2)
Nephropathy in sickle cell disease patients The pathophysiology of renal failure and nephropathy in SCD patients is not yet fully understood
Summary
Sara Bahadoram[1] ID , Bijan Keikhaei[1] ID , Mohammad Bahadoram[1,2] ID , Mohammad-Reza Mahmoudian-Sani[1,2] ID , Shakiba Hassanzadeh3* ID
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