Abstract
Background The association of renal cell carcinoma and Kartagener's syndrome is unusual, and only eleven cases have been reported in the literature. The purpose of this work is to analyze this unusual association of Kartagener's syndrome and renal cell tumor and to study the main diagnostic and therapeutic aspects through our observation and review of the literature. Case Presentation. We report the case of a 50-year-old patient, with a history of recurrent respiratory infections, in whom a renal tumor was simultaneously diagnosed with Kartagener's syndrome, represented by situs inversus, bronchiectasia, and chronic sinusitis. The patient was treated by partial nephrectomy, and the histological examination showed a clear cell carcinoma. Through this observation and a review of the literature, we try to analyze this association as well as the main diagnostic and therapeutic aspects. Conclusion The association of situs inversus and renal cell carcinoma is very rare—preoperative assessment and anatomy knowledge are crucial for a better adaptation of the surgical technique.
Highlights
The association of renal cell carcinoma and Kartagener’s syndrome is unusual, and only eleven cases have been reported in the literature
Bronchiectasis, chronic sinusitis, and situs inversus are the classic three abnormalities. This syndrome is a part of primary ciliary dyskinesias (PCD), a rare genetic group of diseases that involve a constitutional abnormality of the cilia leading to respiratory damages [1, 2]
We report a case of renal cell carcinoma (RCC) discovered in a patient with Kartagener’s syndrome
Summary
The association of renal cell carcinoma and Kartagener’s syndrome is unusual, and only eleven cases have been reported in the literature. We report the case of a 50-year-old patient, with a history of recurrent respiratory infections, in whom a renal tumor was simultaneously diagnosed with Kartagener’s syndrome, represented by situs inversus, bronchiectasia, and chronic sinusitis. The patient was treated by partial nephrectomy, and the histological examination showed a clear cell carcinoma Through this observation and a review of the literature, we try to analyze this association as well as the main diagnostic and therapeutic aspects. The association of renal cell carcinoma and Kartagener’s syndrome is unusual, and only 11 cases have been reported in the literature
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