Abstract

IgA nephropathy (IgAN) is a common diagnosis in patients undergoing renal biopsy for hematuria and proteinuria, but histopathology may vary widely among affected patients. Worldwide, IgAN is the most common form of primary glomerulonephritis and is a leading cause of end-stage renal failure in patients presenting for renal replacement therapy. In the United States, prevalence rates of IgA nephropathy are only 2 to 10 percent while in Asia prevalence rates range from 20 to 40%. In Chin refugees relocated from Myanmar (formerly Burma) to a geographic area near our laboratory in the Midwestern United States (U.S.), IgAN was the most frequently encountered glomerulopathy detected in needle biopsy specimens. We report our biopsy experience with this small but unique cohort, many of whom have had little to no previous access to medical care.

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