Renal Agenesis, Dysplasia, Hypoplasia and Cystic Diseases of the Kidney

Abstract

Renal malformations represent the most common manifestation of congenital diseases in childhood. Renal agenesis, dysplasia, hypoplasia and cystic renal diseases are such entities. Causes vary; partially they derive from the complex renal organogenesis, and partially they have genetic and inherited reasons. Furthermore, an acquired disease can be present. Today there is increasing evidence that disturbances of the ciliumcentrosome complex form the pathogenetic base of most or many phenotypically different cystic renal diseases on a cellular level (Guay-Woodford 2006). The knowledge of the individual etiology and development helps to understand the disease process, affects further diagnostic and therapeutic management and helps to properly estimate prognosis of these patients and their families, respectively.KeywordsAutosomal Dominant Polycystic Kidney DiseasePolycystic Kidney DiseaseRenal CystCystic DiseaseRenal AgenesisThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.