Abstract

To the Editor.— The association between eruptive seborrheic keratoses and internal malignancy has been reported before 1 and given the name of Leser-Trelat sign. 2 In previous reports the affected organs were as follows: adenocarcinoma of the stomach, four cases 3 ; adenocarcinoma of the large intestine, four cases 4 ; and adenocarcinoma of pancreas, 3 breast, 3 ovary, 1 uterus, 2 and prostate, 5 one case each. One patient had a squamous cell carcinoma of the lung 6 and one had Sezary syndrome. 1 Most of the patients were well over the age of 50 years. The time of eruption was short (between one and seven months). Report of a Case.— A 62-year-old woman was hospitalized for paresthesia and progressive weakness of the legs. During the previous five months she had noted onset of a large number of skin lesions on the head and trunk. On examination, multiple seborrheic keratoses were

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