Removal of sulfonamide antibiotics and human metabolite by biochar and biochar/H2O2 in synthetic urine

Abstract

Source-separated urine has been increasingly regarded as a promising alternative waste-stream for effectively removing pharmaceuticals and human metabolites. This study investigated the removal of sulfonamide antibiotics, one category among the most frequently detected antibiotics in the environment, by biochar and biochar/H2O2 in synthetic urine matrix. The adsorption and degradation of four parent sulfonamide antibiotics, including sulfamethoxazole, sulfadiazine, sulfamethazine, sulfadimethoxine, and one human metabolite, N4-acetyl-sulfamethoxazole (together referred as SAs) were investigated. Biochar derived from cotton straw was applied as adsorbent for SAs and catalyst for H2O2. Results showed that the adsorption of SAs was inhibited in urine compared with that in phosphate buffer solution. Bicarbonate in urine placed major influence. Langmuir isotherm model well described the adsorption process in both buffer and urine matrices. Adsorption and desorption rates were estimated by a kinetic model, which well fitted the removal of SAs from aqueous phase at various biochar doses. The adsorption of SAs on biochar was due to multiple forces, in which van der Waals forces and hydrophobicity played major roles in distinguishing the sorption behavior of different SAs. To destruct the SAs, H2O2 was added with biochar. Except for N4-acetyl-sulfamethoxazole, all the parent SAs can be degraded in urine matrix. Carbonate radical, produced from the activation of peroxymonocarbonate by biochar, was proposed to be the major contributing reactive species in biochar/H2O2 system in urine matrix.