Removal of endocrine disrupters from the contaminated environment: public health concerns, treatment strategies and future perspectives - A review

Abstract

Endocrine-disrupting compounds (EDCs) are emerging contaminants of concern (ECC) that disturb endocrine hormones and system functionality even at very low concentrations (i.e. μg/L or ng/L levels). Hence, EDCs are found in all components of the environment including surface and groundwater, wastewater, soil, outdoor and indoor air and in the contaminated foods from a variety of sources (run off from agricultural activities, sewage treatment plants, leakage from septic tanks etc.), and the effects are more severe as the majority of EDCs do not have standard regulations. The environmental mobility of EDCs is higher as conventional wastewater treatment does not degrade efficiently and the development of effective and sustainable removal technologies specifically designed for the removal of those emerging micropollutants is essential. Accordingly, EDCs cause various public health diseases such as reproductive abnormalities, obesity, various cancer types, cardiovascular risks, metabolic disorders, epigenetic alterations, autism, etc. This paper reviews the existing and emerging treatment technologies for the removal of phenolic based EDCs, such as natural estrogens (estrone (E1), 17β-estradiol (E2), estriol (E3)), synthetic estrogen 17α-ethinylestradiol (EE2) and phenolic xenoestrogens (4-nonyl phenols (4-NP) and bisphenol-A (BPA)) from the contaminated environment. These includes advanced oxidation processes (AOP), adsorption processes, membrane based filtration, bioremediation, phytoremediation and other integrated approaches. The sustainability of EDCs removal can be assured through the use of combined processes (i.e. low-cost - biological and adsorption methods with efficient and costly - AOPs) techniques through system integration to achieve better removal efficiency than using a single treatment technique. Besides, the public health concerns and future research perspectives of EDCs are also highlighted.