Abstract

Introduction: the purpose of this study was to perform a systematic histologic analysis of an allogeneic biologic scaffold explanted from abdominal wall repair sites of human subjects at the time of a clinically-indicated abdominal re-exploration. We hypothesized that higher collagen type I:III ratios and more favorable remodeling scores of explanted scaffolds would inversely correlate with subject Charlson Comorbidity Index (CCI), ACS Wound Class, and CDC National Nosocomial Infections Surveillance (NNIS) Risk Index assessed at time of both scaffold implantation (T1) and explantation (T2).

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