Abstract
The etiology of CD is unknown, but several proven riskfactors exist such as family history, smoking, oral contra-ceptives, diet and ethnicity. The combination of risk factors,and aberrant autoimmune response in the intestinal mucosawith endothelial dysfunction lead to digestive tract malfunc-tioning. Disease manifestations are heterogeneous but mostpatients present with abdominal pain, diarrhea sometimeswith blood, weight loss, fever and perianal lesions. Up to 30%of
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