Abstract
Aim: To review the effect of recently developed remineralization materials as well as fluorides on enamel and dentin surfaces of non-carious lesions exposed to various erosive agents. Materials and Methods: This review has been clearly aligned with the preferred reporting items for systematic reviews and meta-analyses (PRISMA). Research on literature has been carried out using online databases such as PubMed/MEDLINE, Scopus, Google Scholar, and Cochrane databases to identify studies published from 2008-2023 (december) by screening titles and abstracts, and making obligatory exclusions after applying eligibility criteria. The QUIN Tool was used to assess potential biases. Results: The final count of studies included in the review was 23. The average surface roughness and surface microhardness showed substantial variances after the application of remineralizing agents on artificially induced non-carious lesions by erosive agents. Discussion: It could be concluded that fluorides still pertain to be the most beneficial with titanium and stannous fluoride showing immense protective effects. Casein phosphopeptide-amorphous calcium phosphate combined with fluorides also showed positive effects on enamel, and dentin surfaces and varied in their mode of action on primary teeth.
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