Abstract

Dental caries is a highly prevalent multifactorial disease and has been a major public health problem for many centuries. The goal of modern dentistry is to manage non-cavitated caries lesions non-invasively through remineralization in an attempt to prevent disease progression and improve aesthetics, strength, and function. Remineralization is defined as the process whereby calcium and phosphate ions are supplied from an externalsource to the tooth thereby converting ion deposition into crystal voids in demineralized enamel, thus producing net mineral gain. Biomimetic approaches to stabilization of bioavailable calcium, phosphate, and fluoride ions and the localization of these ions to non-cavitated caries lesions for controlled remineralization shows great promise for the non-invasive management of dental caries. The aim of this article is to give a brief update about current remineralization agent aiming to “treat early caries lesion noninvasively.

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