Remdesivir: A Critical Review of Pharmacology and Clinical Efficacy to Treat Covid 19

Abstract

The global pandemic of SARS- CoV- 2, the causative viral pathogen of COVID- 19, has driven the biomedical community to action to uncover and develop antiviral interventions. One implicit remedial approach presently being estimated in multitudinous clinical trials is the agent remdesivir, which has endured a long and winding experimental path. Remdesivir as a medicine attracted a veritably serious consideration of whole Globe in treatment of the epidemic complaint COVID19. More lately published in- vitro inhibition exertion and in- vivo case studies were showing promising clinical results and outgrowth of effective inhibition of SARS- CoV- 2 contagion by the use of remdesivir. Still at the same time, use of the remdesivir showed substantial mischievous adverse events in cases which needs a special attention during treatment course of COVID- 19. Therefore, the use of remdesivir in treatment of COVID- 19 is having current transnational interest although some further clinical attestations are still necessary in order to understand the factual effectiveness and medium of remdesivir against COVID- 19.. Ok n this review composition, we give an overview of remdesivir’s discovery, Pharmacology including medium of action, and The Current Studies Exploring Its Clinical Effectiveness.