Abstract
Arguments are given about the expediency of early enteral treatment in life-threatening conditions to improve the functions of the intestinal barrier structures, prevent the transformation of the symbiotic microbiome phenotype and translocation of its representatives with the formation or aggravation of a systemic inflammatory response. The expediency of including proteins and beta-glucans and phosphates in the composition of nutritional mixtures was determined. For the purpose of pharmacological support, the possibility of including iron skevingers, valproates as histone acetylase inhibitors, antioxidants, statins and infusion solutions enriched with hydrogen was considered. The implementation of the paradigm of early enteral nutrition will improve the prognosis of patients in intensive care units.
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