Abstract

Background: Since development of the first COVID-19 vaccine, the landscape of public confidence in these vaccines is uncertain. Building confidence is crucial for better preparedness of future pandemics. Following the mandatory COVID-19 vaccination policy in the country, the aim of this study was to examine whether the Saudi public feels relieved post-vaccination and to identify the factors predicting such relief.Methods: An online cross-sectional survey was conducted in July 2021 among COVID-19 vaccine recipients in Saudi Arabia. A multivariable logistic regression analysis was employed to examine and identify the variables associated with feeling relieved post-vaccination.Results: Most of the respondents (66%) stated feeling more relieved post-vaccination. Male gender [adjusted odds ratio (AOR): 1.380; 95% confidence interval (CI): 0.981–1.943], being a student (AOR: 3.902; 95% CI: 1.674–9.096), and received two doses of the vaccine (AOR: 2.278; 95% CI: 1.630–3.182) were associated with feeling more relieved after getting vaccinated. Respondents who were anxious about the vaccine before receiving it (AOR: 0.220; 95% CI: 0.160–0.302), and experienced a severe reaction after vaccination (AOR: 0.288; 95% CI: 0.165–0.504) had lower odds of feeling relieved post-vaccination. Respondents who relied on social media as the main source of vaccine-related information and those having no information about the vaccine were also less likely to feel relieved post-vaccination.Conclusions: Individuals' attitudes toward COVID-19 vaccines may not necessarily alter post-vaccination. Although mandatory vaccination policies can significantly contribute to achieving herd immunity, public confidence toward vaccines might be eroded, which could in turn impose significant challenges in future pandemics efforts.

Highlights

  • It is well-recognized that mass immunization efforts represent a critical step toward combating the COVID-19 pandemic [1]

  • The challenge of a vaccine-based solution to the COVID-19 pandemic does not end with the development of an effective and safe vaccine, as achieving herd immunity will require the vaccination of a significant proportion of the population [1]

  • Three-quarters of the participants indicated that the official media and scientific or medical websites were their main sources of information about COVID19 vaccines

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Summary

Introduction

It is well-recognized that mass immunization efforts represent a critical step toward combating the COVID-19 pandemic [1]. The development of COVID-19 vaccines has shown the world how substantial funding, research collaboration, and diligence can stimulate innovation to address public needs at a global level and in a short period of time [2]. The challenge of a vaccine-based solution to the COVID-19 pandemic does not end with the development of an effective and safe vaccine, as achieving herd immunity will require the vaccination of a significant proportion of the population [1]. Enhancing public trust in COVID-19 vaccines and vaccination in general is as critical as developing effective vaccines [2]. Since development of the first COVID-19 vaccine, the landscape of public confidence in these vaccines is uncertain. Following the mandatory COVID-19 vaccination policy in the country, the aim of this study was to examine whether the Saudi public feels relieved post-vaccination and to identify the factors predicting such relief

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