Abstract

PurposeTo review our experience in ultrasound fetal weight estimation in our large population of triplet pregnancies.MethodsNinety-seven triplet pregnancies were retrospectively included between January 2003 and January 2017. Sonographic fetal weight estimation using Hadlock’s and Schild’s formulas was compared to actual birth weight in a tertiary-care center in Vienna, Austria. Statistical analyses were performed using a stepwise linear regression model and crosstabs.ResultsThe median discrepancy between the sonographically estimated fetal weight by Hadlock’s formula and the actual birth weight was 106 g (IQR 56–190). The percentage error and its standard deviation were − 2.5 ± 12.1%, and the median percentage error was − 3.6%. Concerning the use of Hadlock’s formula, estimated fetal weight was the most important factor predictive of actual birth weight with an estimate of 0.920 (p < 0.001). Female neonates had been overestimated by a mean of 50.473 g per fetus. The sonographic prediction of small-for-gestational-age neonates was significantly reliable (p < 0.001), with positive and negative predictive values ranging from 81.3 to 100.0%. Similar results were obtained for Schild’s formula.ConclusionEven if sonographically estimated fetal weight in triplet pregnancies has a high overall accuracy of fetal weight estimation, there are some limitations in prediction of intrauterine growth restrictions, especially in female fetuses.

Highlights

  • In times of increasing number of multiple pregnancies that include triplets [1], clinical knowledge of these issues needs to be expanded

  • Exact sonographic estimation of fetal weight before delivery is essential in these pregnancies for several reasons: triplet pregnancies are associated with high rates of preterm deliveries [2,3,4,5]; and the teams on the neonatal intensive care units need the information before

  • Birth-weight discordance is common among multiple pregnancies [6]

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Summary

Introduction

In times of increasing number of multiple pregnancies that include triplets [1], clinical knowledge of these issues needs to be expanded. Accuracy depends on clinical experience, surrounding factors including the time interval between weight estimation and delivery, and quality of the equipment [10]. Birth-weight discordance is common among multiple pregnancies [6]. The question arises whether ultrasound is a reliable method in triplet pregnancies. Evidence about the accuracy of sonographically estimated fetal weight in triplet pregnancies is scarce [8,9,10,11,12,13]. Good correlations between estimated fetal weight and actual birth weight have been

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