Reliability of Periodontal Pathogens and Human Cathelicidine Ll-37 in the Prediction of the Different Stages of Periodontal Disease

Koshy Philip

doi:10.31031/mrd.2019.04.000588

Abstract

Reliability of Periodontal Pathogens and Human Cathelicidine Ll-37 in the Prediction of the Different Stages of Periodontal Disease

Highlights

Periodontal diseases are basically classified into two types that include gingivitis and chronic periodontitis
LL-37 in Gingival crevicular fluid (GCF) may be considered as relevant biomarker for chronic periodontitis
Many studies have demonstrated that the composition of subgingival pathogens amongst different populations in the world is important to provide information into the bacterial changes during the different stages of periodontal disease progression that occurs in individuals from different geographical regions [25]

Summary

Introduction

Periodontal diseases are basically classified into two types that include gingivitis and chronic periodontitis Both diseases are essentially caused by bacteria present in the subgingival biofilm. It has been proven that there are variances in the distribution of periodontal bacteria among different populations [4] Along with these findings, the majority of these bacterial species that are present in the normal periodontal microbiota will further complicate the determination of microbial profiles in subgingival plaque [5]. Five microbial complexes repetitively exist in the subgingival biofilm of individuals with and without periodontal inflammation [8]. This comprises the red complex which encompasses a conglomerate of three species namely Porphyromonas gingivalis, Tannerella forsythia and Treponema denticola

Objectives

Methods

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Discussion

Conclusion