Abstract
Purpose To assess the accuracy of pachymetric measurements using Orbscan (Bausch & Lomb, Rochester, NY) after laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK). Design Prospective instrument validation study. Participants Seventy-nine nonoperated normal eyes, 84 eyes after LASIK, and 50 eyes after PRK. Intervention Laser in situ keratomileusis or PRK. Methods Central corneal thickness was measured using ultrasound and Orbscan II. The acoustic factor (AF) was adjusted, based on the results obtained in the normal eye group, to minimize the difference between ultrasound and Orbscan pachymetric values. Main outcome measures Central corneal thickness as measured by Orbscan and ultrasound pachymeter. Results Using the adjusted AF, which was 0.946, the mean difference between Orbscan and ultrasonic pachymetric measurements was 0 ± 17, 16 ± 28, and 68 ± 39 μm in the normal, LASIK, and PRK groups, respectively. The difference between all groups was statistically significant ( P < 0.0001). Conclusions Orbscan pachymetric values may be underestimated and less accurate after LASIK and PRK.
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