Abstract
Abstract Background The prevention of cardiovascular disease (CVD) is important in clinical practice due to its high morbidity and mortality. Different guidelines have recommended the use of different cardiovascular risk assessment tools, which may have implications on therapeutic decisions. Objective To evaluate the agreement rate between the Framingham risk score (FRS) and the Systematic Coronary Risk Evaluation (SCORE) tool on CVD risk assessment in disease-free subjects. Methods Cross-sectional study with a sample of 51 subjects treated at the outpatient clinic [...]
Highlights
The proportion of hypertension was similar between genders {female and male [45.5% (15/33) vs. 50% (9/18), p = 0.96]}; a higher prevalence of diabetes mellitus (DM) was observed in men [44.4% (8/18) vs. 18.2% (6/33), p = 0.057]
According to the Framingham risk score (FRS), 35.3% [18/51] of the participants had a high cardiovascular risk, whereas 23.5% [12/51] of the subjects were classified as having a high risk of fatal cardiovascular disease (CVD) in 10 years according to the Systematic Coronary Risk Evaluation (SCORE)-High
This value dropped to 13.7% [7/51] when the SCORE for low-risk European countries (SCORE-Low) was used (Graph 1)
Summary
Cardiovascular disease (CVD) is a major cause of morbidity and mortality and cause of 17.1 million deaths worldwide, which corresponds to 45% of deaths for chronic noncommunicable diseases. In Brazil, CVD is responsible for approximately 20% of deaths in people older than 30 years, and in 2015 it represented an estimated total cost of BR 37.1 billion.2,3CVD prevention is crucial in clinical practice, and identifying asymptomatic subjects at high risk is essential for an effective prevention. To meet this demand, cardiovascular risk assessment tools, and risk scores, including the Framingham risk score (FRS), have been the most widely used worldwide. it is known that these tools have limitations and may overestimate the risk in certain populations, which prompted the development of other scores. For example, the Systematic Coronary Risk Evaluation (SCORE), created based on the results of 12 European cohort studies, has been recommended since 2003 by the European CVD Prevention Directive. This score estimates the 10-year risk of fatal CVD relying on a model that encompasses countries with high and low incidence of CVDs (SCORE-High and SCORE-Low, respectively).. CVD prevention is crucial in clinical practice, and identifying asymptomatic subjects at high risk is essential for an effective prevention.4,5 To meet this demand, cardiovascular risk assessment tools, and risk scores, including the Framingham risk score (FRS), have been the most widely used worldwide.. The Systematic Coronary Risk Evaluation (SCORE), created based on the results of 12 European cohort studies, has been recommended since 2003 by the European CVD Prevention Directive.. The Systematic Coronary Risk Evaluation (SCORE), created based on the results of 12 European cohort studies, has been recommended since 2003 by the European CVD Prevention Directive.5 This score estimates the 10-year risk of fatal CVD relying on a model that encompasses countries with high and low incidence of CVDs (SCORE-High and SCORE-Low, respectively).. Conclusions: There was a high agreement rate between FRS and SCORE-High in cardiovascular risk assessment in the study sample. (Int J Cardiovasc Sci. 2020; 33(6):618-626) Keywords: Cardiovascular Diseases/prevention and control; Risk Factors; Mortality; Morbidity; Hypertension; Diabetes; Risk Assessment; Cross-Sectional Studies
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