Abstract

We compared the reliability and response time (RT) of three patient triggered infant ventilators in 10 healthy adult rabbits. Ventilation was randomly assigned to a Bear Cub Enhancement Module (CEM), Infrasonics star Sync, and Draegar Babylog 8000 in both the synchronized intermittent mandatory ventilation (SIMV) and assist-control (A/C) modes. All studies were repeated at ventilator flow rates of 6 and 12 1pm, and at 3 sensitivity settings (except Star sync). Rabbits were lightly anesthetized and tracheostomized; airway flow and pressure, and pleural pressure were recorded. RT was measured from the start of each spontaneous breath to the onset of each triggered ventilator breath (N=250±50 breaths). Ventilator breaths occurring >200 msec after the start of spontaneous breaths or during early expiration were considered trigger failures and were excluded from analysis for RT. RT (mean±SD) and failure rate at maximum sensitivity and 12 1pm were compared by ANOVA: RT of each ventilator was the same at 6 and 12 1pm in both modes. RT of star Sync was shorter than Bear CEM, and Bear CEM was shorter than Babylog on both modes (p<.01). Decreasing trigger sensitivity by 2 settings increased RT of both Bear CEM and Babylog by 60%. The Babylog failed consistently on SIMV but not at all on A/C.

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