Abstract
Abstract Background The storage of different biomaterials over long time periods is one of the main requirements of biobanking ensuring that modifications in the composition or any other change of the biomaterials have to be avoided. In the German National Cohort samples from around 200,000 participants are processed and stored long term. Methods A tender for cryotubes and racks was performed in 2013 setting up several characteristics that were judged against each other. Tubes and racks were evaluated regarding the performance and handling in connection with the main biorepository. With a 5-year experience using the selected tubes we are able to reflect some of the criteria of the tender. Results At the end of the decision, the former company FluidX, in the meantime taken over from Brooks (Brooks Life Sciences, Manchester, UK), received the order. The experience with the external testing of the tube was useful. Conclusions Overall, the experience with the cryotubes is good and their mechanical handling at the different sites is routine in the meantime. There are some aspects that we recommend for future tenders. Further research is necessary to learn more about the cryotubes and the labware in general in the field of biobanking to store our samples as safely as possible.
Highlights
The storage of different biomaterials over long time periods – up to decades – is one of the main requirements of biobanking
Overall, the experience with the cryotubes is good and their mechanical handling at the different sites is routine in the meantime
There are some aspects that we recommend for future tenders
Summary
The storage of different biomaterials over long time periods – up to decades – is one of the main requirements of biobanking. One of the approaches to achieve this goal is the storage at low temperatures, down to around −195 °C in the gas phase of liquid nitrogen These low temperatures have positive effects in view of the sample quality, but the applied container for the biomaterials needs specific properties. In 2013 the German National Cohort (GNC) performed a tender for the cryotubes of the GNC. Within the GNC around 200,000 participants were recruited in the meantime in 18 study centres around Germany [1]. The storage of different biomaterials over long time periods is one of the main requirements of biobanking ensuring that modifications in the composition or any other change of the biomaterials have to be avoided. The experience with the external testing of the tube was useful
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