Abstract

AbstractN‐glycosides are produced when an aglycone is connected, for example, using a glycosylation reaction, to the sugar moiety via linkage of C−N bond at anomeric carbon. N‐glycosides are obtained from different precursors, including glucals, 1‐azido glycosides, glycosyl azide, glycosyl isothiocyanate, 2‐deoxy‐2‐iodo‐N‐glycoside, glycosyl‐1H‐1,2,3‐triazol, and 2‐nitroglucal. The biological relevance of N‐glycopyranosides has drowned attracted the attention of several researchers. The scope of this review covers the literature from 2010 to 2022. Recent advances focused on the natural occurrence, synthesis, mechanism, and pharmacological applications of N‐glycopyranosides are discussed.

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