Abstract
Mango fruits and mango leaf extracts (Mangifera indica) are a medicinal plant used to treat diabetes and its complications. The tender leaves of the mango tree contain tannins called anthocyanidins, which help treat early diabetes. The leaves contain the compound 3 betataraxerol and ethyl acetate extract, which interacts with insulin, activating GLUT4 and stimulating glycogen synthesis. Mango leaves have powerful antioxidant properties because they contain a large amount of flavonoids, phenols, zeaxanthin and beta-carotene. Animal studies have shown that mangiferin can counteract the free radical associated with cancer, diabetes, and other diseases.
Highlights
Плоди манго та екстракти листків манго (Mangifera indica) є лікарським засобом, який використовують для лікування діабету і його ускладнень
Mangiferin has a therapeutic potential against lifestyle disorders
Mangiferin protects against cancer of the nervous system and breast cancer by inhibiting the expression of matrix metalloproteinase (MMP)-9 and MMP-7 and inhibiting the enzymatic activity, metastatic potential and activation of the β-catenin pathway
Summary
Плоди манго та екстракти листків манго (Mangifera indica) є лікарським засобом, який використовують для лікування діабету і його ускладнень. Mangiferin protects against different human cancers, including lung, colon, breast, and neuronal cancers, through the suppression of tumor necrosis factor α expression, inducible nitric oxide synthase potential, and proliferation and induction of apoptosis.
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