Abstract
This study describes the relevance of human chromosome analysis activities against genes and cromosomes mutation in genetics course. This activities is to analyze the images of photomicrograph chromosomes of various cases and disorders caused by irregularities of human chromosome number or structure in the form of a karyotype. The purpose of this analysis is to gain relevance practicum against the theory course. Object of this research is the lab activities of analysis human chromosomes. Source of data derived from syllabus documentation, SAP, genetics lecture, lab instructions, journals genetics, and 40 respondents taken by purposive sampling. The results showed analysis of human chromosomes activities can only preach of chromosome mutation concept only. The use of inquiry-based lab project can be to preach more concept of gene mutations with more knowledge coverage, the allocation of more time, greater cost, fewer students so that it matches given to undergraduate student biology deepen molecular genetics. Conclusion of this studies, analysis of human chromosomes activities is relevant to preach human chromosome mutation concept but can not be used to preach concept of gene mutations
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