Release of mitochondrial respiratory control by cyanate salts

Abstract

Mitochondrial respiration is stimulated by 5–40 mM potassium cyanate in the presence or absence of oligomycin. When the cyanate concentration is increased over 40 mM, the mitochondria respire at progressively lower rates. In these respects, although at relatively high concentrations, cyanate behaves as an uncoupler of oxidative phosphorylation.