Abstract
1. Pretreatment of isolated eyestalk tissues of the fiddler crab, Uca pugilator, with drugs that interfere with norepinephrinergic neurotransmission, alpha-methyl- p-tyrosine, fusaric acid, 6-hydroxy-dopamine, and bretylium, prior to electrical stimulation resulted in the release of significantly less black pigment-dispersing hormone (BPDH) and light-adapting hormone (LAH) than from tissues that had been kept in saline alone prior to being electrically stimulated. 2. These data support the hypothesis that norepinephrine has a physiological role in stimulating release of BPDH and LAH in the fiddler crab.
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