Abstract
AbstractLymphocytotoxic antibody activity of dera from 23 patients with systemiclupus erythematosus (SLE) was compared using three different sets of lymphocytes‐peripheral blood lymphocytes from 20 normal controls, perpheral blood lymphocytes from 10 patients with chronic lymphocytic leudemia (CLL) and thymic [thymus‐derived (T)] cells of 5 human fetuses. A marked decreased reactivity of the SLE sera with CLL lymphocytes and marked increased reactivity with fetal thymic cells as compared to controls was found. These data suggest T‐cell specificity of lymphoctotoxic antibodies in SLE.
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