Abstract

This cohort study aims to compare the performance of alternative frequency weightings of hand-transmitted vibration (HTV) for the assessment of the exposure-response relationships for neurosensory disorders and reduced work ability among HTV-exposed workers. In a 3-year follow up study, the occurrence of neurosensory symptoms and reduced work ability, and the response to quantitative sensory testing (grip force, manipulative dexterity, touch sensation) were investigated in 249 HTV-exposed workers and 138 healthy controls. Among the HTV-exposed workers, the sensory outcomes were related to measures of daily vibration exposure expressed in terms of 8-hour energy-equivalent frequency-weighted acceleration magnitude [A(8)]. To calculate A(8), the acceleration magnitudes of vibration were weighted by means of four alternative frequency weightings of HTV. The occurrence of neurosensory symptoms, reduced work ability, and abnormalities of sensory tests was greater among the HTV-exposed workers than the controls. Among the HTV-exposed workers, the deterioration of neurosensory outcomes and the reduction of work ability increased on par with the measures of vibration exposure. Exposure-response models revealed that the four alternative frequency weightings of HTV provided the same predictions for the probability of finger numbness among the exposed workers (observed 36% versus predicted 32%). The findings of this study revealed significant dose-response relationships between measures of vibration exposure, sensory disorders, and reduced work ability among the HTV-exposed workers. There were no differences in the prediction of finger numbness between measures of vibration exposure calculated with alternative frequency weightings of HTV.

Highlights

  • There were no differences in the prediction of finger numbness between measures of vibration exposure calculated with alternative frequency weightings of handtransmitted vibration (HTV)

  • In the international standard ISO 5349-1 [2] for the evaluation of human exposure to HTV, it is said that the exposure–response relationship proposed in an annex to the standard may be used for the assessment of all biological effects of HTV

  • The acceleration magnitude of vibration is frequency weighted over the working frequency range specified in ISO 5349-1 by means of a weighting function which assumes that the sensitivity of the finger-hand-arm system is approximately proportional

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Summary

Methods

In a 3-year follow up study, the occurrence of neurosensory symptoms and reduced work ability, and the response to quantitative sensory testing (grip force, manipulative dexterity, touch sensation) were investigated in 249 HTV-exposed workers and 138 healthy controls. Among the HTV-exposed workers, the sensory outcomes were related to measures of daily vibration exposure expressed in terms of 8-hour energy-equivalent frequency-weighted acceleration magnitude [A(8)]. The cohort included 249 HTV-exposed workers (215 forestry operators and 34 stone workers) and 138 control men employed at the same companies and unexposed to HTV (129 maintenance operators, 5 inspectors, 4 supervisors). They were investigated at the cross-sectional survey and over annual follow-up investigations carried out in the same seasonal period (autumn–winter 2003–2007). A complete description of the cohort and the study design has been reported in a previous paper [7]

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