Relationships of liver biochemical parameters and effects of wine drinking

Abstract

Generally dietary factors may influence liver biochemical parameters. It is well known that wine drinking is a principal risk factor for liver-disorder. Alcoholic cirrhosis is a liver disease which is due to excessive alcohol intake. OBJECTIVES: Epidemiological research often seeks to identify whether a causal relationship exists between the risk factor and the disease. Mechanisms of alcohol intake of the human body are intricately complicated. These mechanisms, however, can be easily interpreted through appropriate mathematical relationships. This article focuses to establish a association between liver biochemical parameters and wine drinking. RESULTS: The present analyses show that wine drinking has individual, interaction and confounding effects on all the compo- nents of liver biochemical markers. In the process, it establishes the relationship of each biomarker with wine drinking and the remaining other biomarkers. Effects of wine drinking on each component of liver biomarkers are identified. CONCLUSIONS: Impacts of wine drinking on liver biomarkers are explained based on mathematical relationships. Mathemati- cal relationships of liver biomarkers present the functional activity of each biomarker on the others. These analyses support many earlier researches findings. However, the present analyses also identify many additional casual factors that explain the mean and variance of each liver biochemical marker, which earlier researches have not reported.