Abstract
Adult female Sprague-Dawley rats were implanted with chronic cortical and temporalis muscle electrodes and/or intravenous cannulas. After acute ethanol administration, dose-dependent linear declines in blood ethanol concentration were found. Ethanol-induced increases in EEG spectral power in the 0–4 Hz band persisted long after blood ethanol levels had declined to zero; therefore, we found no correlation. Acute ethanol administration also produced an initial drop in 8–13 Hz spectral power. Then, as blood ethanol levels declined, 8–13 Hz spectral power increased toward normal; a significant negative linear correlation was found.
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