Abstract
BackgroundThe concepts of medication adherence and Treatment satisfactions are commonly used in clinical research for assessing pharmaceutical care and improving treatment outcomes. Generally, one would expect a positive relationship between the two concepts. The objectives of this study were to investigate the factors associated with adherence to antihypertensive therapy among hypertensive patients and to assess the relationship between antihypertensive medication adherence and treatment satisfaction.MethodsA cross-sectional study was conducted, adopting the Morisky eight-item Medication Adherence Scale (MMAS) for the assessment of medication adherence and using the Treatment Satisfaction Questionnaire for Medication (TSQM 1.4) for the assessment of treatment satisfaction. Descriptive and comparative statistics were used to describe socio-demographic and disease-related characteristics of the patients. All analyses were performed using SPSS v 15.0.ResultsFour hundred and ten hypertensive patients were enrolled in the study. The mean age of participants was 58.38 ± 10.65 years; 52% were female and 36.8% had low antihypertensive medication adherence. There was a significant difference in the mean scores in the Effectiveness (p < 0.001), Convenience (p < 0.001), and Global Satisfaction (p < 0.001) domains, but not in the Side Effects (p = 0.466) domain among patients with different levels of adherence. After adjustment for covariates using multiple linear regression, global treatment satisfaction was still statistically significantly (p = 0.001) associated with medication adherence.ConclusionsLow treatment satisfaction may be an important barrier for achieving high rates of adherence to treatment. These study findings could be helpful in clinical practice, mainly in the early treatment of hypertensive patients, at a point where improving treatment satisfaction is still possible.
Highlights
The concepts of medication adherence and Treatment satisfactions are commonly used in clinical research for assessing pharmaceutical care and improving treatment outcomes
Given the small number of studies in which the association between adherence and treatment satisfaction has been investigated [6,10,11], a review of the literature revealed no studies on medication adherence and treatment satisfaction among patients with hypertension in the Arab world. This is important given that culture and religion might play a role in health-related issues; the objectives of this study were to investigate the factors associated with adherence to antihypertensive therapy among hypertensive patients and to assess the relationship between antihypertensive medication adherence and treatment satisfaction
We conclude that participants with low treatment satisfaction are more likely to have lower adherence to antihypertensive medications
Summary
The concepts of medication adherence and Treatment satisfactions are commonly used in clinical research for assessing pharmaceutical care and improving treatment outcomes. The objectives of this study were to investigate the factors associated with adherence to antihypertensive therapy among hypertensive patients and to assess the relationship between antihypertensive medication adherence and treatment satisfaction. Multiple factors that influence patient adherence to prescribed therapies have been illustrated; these include treatment satisfaction, high incidence of adverse effects of blood pressure-lowering drugs, health care system issues, quality of life, socio-demographics, lack of knowledge regarding hypertension, and treatment and clinical variables [5,6,7]. The impact of low treatment satisfaction on medication adherence is of particular alarm in patients with chronic diseases. Measures for assessing treatment satisfaction have been developed [9]
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