Abstract
The relationship between PAT activity and t-PA antigen concentration and their dependence on age, sex, body mass index, lipoprotein metabolism parameters and life style was studied in a subpopulation of the DRECAN Study. PAT activity and t-PA concentration showed a similar dependence on age and sex. The ratio PAI activity/t-PA concentration correlated much better with PAT activity than with t-PA concentration. PAT activity and t-PA concentration were equally strong correlated with body mass index and triglyceride concentration. Both fibrinolytic variables showed no significant differences between smokers and non-smokers. PAT activity as well as t-PA concentration were lower in users of oral contraceptives than in non-users. This result was independent of the relationship between BMI as well as triglyceride concentration on PAT activity and t-PA concentration and not the only responsible factor for the higher PAT and t-PA values in men compared to women. The amount of alcohol and beer per day was a significantly influential factor on PAT activity in men. The high PAT activity in middle-aged men is possibly connected with the described higher prevalence of elevated PAT activity in young postinfarction patients compared with unselected patients.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
