Abstract

Fetal growth restriction syndrome (FGR) is a complex problem and, despite the currently used highly informative methods, which do not exclude both false positive and false negative results of assessing the state of the fetus and the uteroplacental complex, it is necessary to use several differently directed methods. In this area, placental growth factor may be a promising biomarker for detecting abnormalities in fetal growth. Determination of changes in the production and functioning of growth factors at the preclinical stage, possibly, will make it possible to predict the risk and influence its implementation.

Highlights

  • Fetal growth restriction syndrome (FGR) is a complex problem and, despite the currently used highly informative methods, which do not exclude both false positive and false negative results of assessing the state of the fetus and the uteroplacental complex, it is necessary to use several differently directed methods

  • In recent years, increasing importance in the formation of pathological conditions and diseases is given to the fetal growth restriction syndrome, which

  • Fetal growth restriction syndrome occurs in 5.0-17.6% of pregnant women, and the frequency of fetal growth restriction in premature babies is higher, and amounts to 15.7-22% [1,2]

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Summary

Introduction

Fetal growth restriction syndrome (FGR) is a complex problem and, despite the currently used highly informative methods, which do not exclude both false positive and false negative results of assessing the state of the fetus and the uteroplacental complex, it is necessary to use several differently directed methods. In recent years, increasing importance in the formation of pathological conditions and diseases is given to the fetal growth restriction syndrome, which Restrictions of intrauterine growth of the fetus due to a pathological process are unable to achieve normal growth for gestational age, which leads to an increased risk to the fetus, such as distress syndrome or fetal death during pregnancy or childbirth.

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