Relationship of Nodular Gastritis and Helicobacter pylori Infection in Children under Treatment at Gujarat Adani Institute of Medical Science Bhuj, Kutch, Gujarat, India

Abstract

Aim: To report annual experience of 20 children with recurring abdominal pain (RAP), endoscopic findings and the outcome of 2 weeks of treatment with omeprazole, clarithromycin and amoxicillin. Methods: Present Study was performed at Gujarat Adani Institute of Medical science Bhuj, Kutch, Gujarat, India from March 2014 to March 2015. For the duration of a 12- month period, 20 children (12 males and 8 females, aged 7-15 years) underwent endoscopy for assessment of RAP according to Apley's criteria. Every child was screened for the existence of serum specific IgG antibodies against HP antigens using an ELISA quantitative immunoassay method. Statistical analysis was performed with the help of SPSS version 15. Results: Helicobacter pylori (HP) gastritis was evident in 8 (40%) patients of the 20 investigated. In two of the eight duodenitis was also observed. The endoscopic manifestation in five patients out of the eight (62.5%) was characterize by numerous small nodules covering most of the antral area and part of the distal area of the fundus. All patients had no symptoms after duration of two weeks of management which consisted of proton pump inhibitor, clarithromycin and amoxicillin. Conclusion: HP plays a role in childhood peptic ulcer disease. The endoscopic is suggestive of HP which plays a role in childhood peptic ulcer disease.