RELATIONSHIP OF MORTALITY AND MORBIDITY WITH POSTOPERATIVE TROPONIN-I LEVELS IN CHILDREN UNDERGOING CARDIAC SURGERY

Abstract

<h3>Introduction</h3> Intraoperative Intraoperative myocardial damage is a mean determinant of postoperative cardiac dysfunction associated with mortality and morbidity in cardiac surgery (1). Cardiac troponin I (TnI) is a particular predictive marker of myocardial injury in the young population, and its increased levels predict mortality after cardiac surgery (2).The purpose of our study was to evaluate the effect of troponin I on postoperative mortality and morbidity in children undergoing cardiac surgery. <h3>Methods</h3> We prospectively measured Tn I levels (preoperative, at the pediatric intensive care unit arrival, at 24 and 48 hours) in 125 children undergoing cardiac surgery.115 were survivors and 10 were nonsurvivors. Aortic cross clamp time (ACC time), cardiopulmonary bypass time (CPB time), inotropic score, duration ventilation, PICU stay were recorded. <h3>Results</h3> Tn I levels were significantly higher in nonsurvivors at 24 and 48 hours (respectively, p=0,04, p=0,02). ACC,CPB times and inotropic score were higher in nonsurvivors than survivors. <h3>Conclusions</h3> Higher TnI levels are associated with increased morbidity in children undergoing cardiac surgery. <h3>References</h3> <ul><li>1. Eigel P, van Ingen G, Wagenpfeil S. Predictive value of perioperative cardiac troponin I for adverse outcome in coronary artery bypass surgery. Eur J Card Surg 2001;20:544-9.</li><li>2. Momeni M, Poncelet A, Rubay J, et al. Does postoperative cardiac troponin I have any prognostic value in predicting midterm mortality after congenital cardiac surgery. Cardiothorac Vasc Anesth. 2017;31:122-7.</li></ul>