RELATIONSHIP OF HYPERTENSION WITH PATIENTS HAVING DIABETES AT CLINICAL SETUPS OF PAKISTAN

Abstract

Abstract Objective: Hypertension and Diabetes both are the facets of metabolic syndrome, a pathologic condition that usually includes obesity and cardiovascular diseases. While in some patients Diabetes mellitus and hypertension both recurrently occurs and probably have synergistic disadvantageous effects on the cardiovascular system. The objective of the current study was to sort out the potential relationship and the impact of high blood pressure on patients who had diabetes. Design and method: This was a prospective, observational study in which 470 hypertensive patients who had confirmed diagnosis of diabetes type II were enrolled in this study. Samples were from age group of 30–60 years in which 130 males and 340 females were observed. All enrolled hypertensive patients had a diastolic blood pressure greater than 90 mmHg and systolic blood pressure greater than 138mmHg. Results: Findings shows that Calcium Channel Blockers, Angiotensin Converting Enzyme (ACE) Inhibitors and Angiotensin Receptor Blockers (ARBs) are preferred agents for Hypertension associated with type 2 Diabetes. In case if targeted blood pressure is not achieved addition of a thiazide diuretic occurs in regimen because it is the preferred 2nd line therapy for hypertension associated with diabetic patients. In another perspective weight loss also seems to be beneficial in the hypertension associated with obesity and diabetes. Candestran and Lisinopril was the most prescribed drugs in earlier patients with hypertension associated with the type 2 diabetes. Conclusions: According to the research findings with the usage of the prescribed drugs blood pressure was controlled while alteration of drugs has seen in some cases as well. Chlorthalidone, Candestran and Lisinopril were the most prescribed and seen to be most effective.