Abstract
When ongoing research established the relationship between Covid-19 infection and diabetes mellitus, the interest of the clinicians and the anxiety of the patients increased. This evidence-based mini-review aims to determine whether or not patients with diabetes are more prone to getting infected with Covid-19 and how this affects their clinical outcomes. Among the reported Covid-19 cases, 6-14% outpatients, 16-25% inpatients, 32-58% ICU patients, and 31-42% cases with a mortal course had diabetes mellitus. The latest meta-analysis did not consider diabetes as a risk factor contributing to the increase in mortality of Covid-19 cases.
Highlights
Covid-19 infection, which emerged in December 2019 in China, continues to spread all over the world
Are diabetic patients more likely to get infected with Covid-19 than non-diabetic patients? Is the clinical course of Covid-19 infected patients with diabetes more severe? Is the mortality rate in diabetes patients higher? Is there a necessity to adjust and/or change the treatment guidelines of diabetic patients infected with Covid-19? With the help of the latest literature about Covid-19, this mini-review will try to address all the questions above and give an insight into the issue
It claimed that in poorlycontrolled diabetes, lymphocyte proliferation is inhibited, activation of complement cascade decreases [5,6], the viral replication increases [7], and the forced vital capacity decreases [8]. 29 diabetic inpatients who received Covid-19 treatment in China were evaluated retrospectively, and in 69% of these patients, glucose levels were high according to their 811 measured blood glucose levels [9]
Summary
Covid-19 infection, which emerged in December 2019 in China, continues to spread all over the world. A meta-analysis from China states that in 2108 Covid-19 infected patients, the rate of diabetes (10.3%) [1], is similar to that of the normal population in the same region (10.9%) [2]. One Chinese research states that among 40 Covid-19 infected patients, 20 cases developed hyperglycemia according to diabetes criteria. This relates to the viral cytopathogenic effect on ACE-2 receptors that are abundant in the pancreas [12]. A Chinese meta-analysis, that included 30 kinds of research, established an association between diabetes, mortality, severe Covid-19 infection, and ARDS [13] Another Chinese meta-analysis involving 1558 patients displays hypertension, diabetes and chronic obstructive lung disease, cardiovascular and cerebrovascular diseases as independent risk factors [14].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
